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Recurrent hypoglycaemia in a patient with thyrotoxicosis due to Insulin autoimmune syndrome

Authors:

S. Sureshkumar ,

National Hospital Sri Lanka, LK
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General Medical Unit
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W. W. L. A. Jayanaga,

National Hospital Sri Lanka, LK
About W. W. L. A.
General Medical Unit
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R. B. A. T. Dulanjalie,

National Hospital Sri Lanka, LK
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General Medical Unit
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S. A. P. N. Samarasingha,

National Hospital Sri Lanka, LK
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General Medical Unit
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H. Karunathilaka

National Hospital Sri Lanka, LK
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General Medical Unit
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Abstract

Insulin autoimmune syndrome (IAS) is an immune-mediated hyperinsulinaemic hypoglycemia in individuals previously unexposed to exogenous insulin. A 63-year-old woman developed recurrent hypoglycemic episodes despite being on optimal glycemic support. She was diagnosed with Graves’ disease and was on carbimazole. Her insulin: C peptide ratio was suggestive of exogenous insulin administration or presence of insulin autoantibodies. Her insulin antibody level was elevated. IAS was probably secondary to her carbimazole therapy.
How to Cite: Sureshkumar S, Jayanaga WWLA, Dulanjalie RBAT, Samarasingha SAPN, Karunathilaka H. Recurrent hypoglycaemia in a patient with thyrotoxicosis due to Insulin autoimmune syndrome. Asian Journal of Internal Medicine. 2023;2(1):71–4. DOI: http://doi.org/10.4038/ajim.v2i1.78
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Published on 07 Feb 2023.
Peer Reviewed

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